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Consortium of Multiple Sclerosis Centers (CMSC) Annual Meeting 2025
Wednesday, May 28, 2025 – Saturday, May 31, 2025
Structural and mechanistic profiling of Nurr1 modulation by vidofludimus enables structure-guided ligand design
Úrsula López-García, Jan Vietor, Julian A. Marschner, Jan Heering, Vasily Morozov, Thomas Wein, Daniel Merk
Communications Chemistry
Published: May 21, 2025
https://doi.org/10.1038/s42004-025-01553-8Digestive Disease Week® (DDW)
Saturday, May 3, 2025 – Tuesday, May 6, 2025
7th Neuroimmunology Drug Development Summit
Tuesday, February 25, 2025 – Thursday, February 27, 2025
Americas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS) Forum 2025
Thursday, February 27, 2025 – Saturday, March 1, 2025
19th Congress of ECCO (European Crohn’s and Colitis Organisation)
Friday, February 19, 2025 – Saturday, February 22, 2025
Vidofludimus Calcium in Patients with Moderate-to-Severe Ulcerative Colitis: A Randomized, Placebo-Controlled, Phase 2 Trial
Geert D’Haens, Kalina Grivcheva Stardelova, Edite Sadiku, Natallia Kizlova, Syitlana Skybalo, Yulia Shehovtsova, Mirela Abramescu, Daniel Vitt, Hella Kohlhof, Andreas Muehler
Clinical and Translational Gastroenterology
Published: January 10, 2025
https://doi.org/10.14309/ctg.0000000000000813Symposium 238: Immuno-Mediated Diseases of the GI Tract: Where Do We Stand?
Friday, November 8, 2024 – Saturday, November 9, 2024
Safety, clinical activity, pharmacodynamics, and pharmacokinetics of IMU-856, a SIRT6 modulator, in coeliac disease: a first-in-human, randomised, double-blind, placebo-controlled, phase 1 trial
A James M Daveson, Richard Stubbs, Thomas M Polasek, Jorma Isola, Robert Anderson, Jason A Tye-Din, Mark Schoeman, Claudette Lionnet, Swee Lin Chen Yi Mei, Jelena Mihajlović, Martina Wirth, Evelyn Peelen, Amelie Schreieck, Hella Kohlhof, Daniel Vitt, Andreas Muehler, Franziska Buriánek
The Lancet Gastroenterology & Hepatology
Published: November 6, 2024
https://doi.org/10.1016/S2468-1253(24)00248-640th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS)
Wednesday, September 18, 2024 – Friday, September 20, 2024
Immunic’s Multiple Sclerosis R&D Day in New York City
Tuesday, September 10, 2024
20th International Celiac Disease Symposium ICDS
Thursday, September 5, 2024 – Saturday, September 7, 2024
DMDG 50th Open Meeting 2024
Monday, September 2, 2024 – Wednesday, September 4, 2024
New developments in celiac disease treatments
Franziska Buriánek, Christian Gege, Petar Marinković
Drug Discovery Today
Published: August 2024
https://doi.org/10.1016/j.drudis.2024.1041132024 Medicinal Chemistry Gordon Research Conference: Advancing Drug Discovery with Innovative Science and Technologies
Sunday, August 11, 2024 – Friday, August 16, 2024
The Consortium of Multiple Sclerosis Centers (CMSC) 38th Annual Meeting
Wednesday, May 29, 2024 – Saturday, June 1, 2024
Digestive Disease Week (DDW) 2024
Saturday, May 18, 2024 – Tuesday, May 21, 2024
Safety and Dose-Response of Vidofludimus Calcium in Relapsing Multiple Sclerosis: Extended Results of a Placebo-Controlled Phase 2 Trial
Robert J. Fox, Heinz Wiendl, Christian Wolf, Nicola De Stefano, Johann Sellner, Viktoriia Gryb, Konrad Rejdak, Plamen S. Bozhinov, Daniel Vitt, Hella Kohlhof, Jason Slizgi, Matej Ondrus, Valentina Sciacca, Andreas R. Muehler
Neurology® Neuroimmunology & Neuroinflammation, an official journal of the American Academy of Neurology
Published: April 25, 2024
https://doi.org/10.1212/NXI.0000000000200208Immunic’s MS R&D Day in San Francisco
Tuesday, April 9, 2024
Frontiers in Medicinal Chemistry
Sunday, March 17, 2024 – Wednesday, March 20, 2024
ACTRIMS Forum 2024
Thursday, February 29, 2024 – Saturday, March 2, 2024
Association of European Coeliac Societies (AOECS) 35th General Assembly Conference 2023
Thursday, November 2, 2023 – Sunday, November 5, 2023
UEG (United European Gastroenterology) Week 2023
Saturday, October 14, 2023 – Tuesday, October 17, 2023
MSMilan2023: The 9th Joint ECTRIMS-ACTRIMS Meeting
Wednesday, October 11, 2023 – Friday, October 13, 2023
16th International Congress of Neuroimmunology (ISNI)
Sunday, August 20, 2023 – Thursday, August 24, 2023
Symposium 234: Mucosal Immunology – A Translational View into the Clinic
Thursday, July 6, 2023 – Saturday, July, 8, 2023
Consortium of Multiple Sclerosis Centers (CMSC) Annual Meeting 2023
Wednesday, May 31, 2023 – Saturday, June 3, 2023
Digestive Disease Week 2023
Saturday, May 6, 2023 – Tuesday, May 9, 2023
Development of a Potent Nurr1 Agonist Tool for In Vivo Applications
Jan Vietor, Christian Gege, Tanja Stiller, Romy Busch, Espen Schallmayer, Hella Kohlhof, Georg Höfner, Jörg Pabel, Julian A. Marschner, and Daniel Merk
Journal of Medicinal Chemistry
Published: April 26, 2023
https://doi.org/10.1021/acs.jmedchem.3c00415Safety, Tolerability, and Pharmacokinetics of IMU-935, a Novel Inverse Agonist of Retinoic Acid Receptor–Related Orphan Nuclear Receptor γt: Results From a Double-Blind, Placebo-Controlled, First-in-Human Phase 1 Study
Thomas M. Polasek, Indika Leelasena, Irina Betscheider, Marija Marolt, Hella Kohlhof, Daniel Vitt, Frank Fliegert, Andreas R. Muehler
Clinical Pharmacology in Drug Development
Published: March 20, 2023ACTRIMS Forum 2023
POSTER PRESENTATION
Thursday, February 23, 2023 – Saturday, February 25, 2023
Immunic’s Celiac Disease R&D Webcast
Thursday, February 09, 2023
Outsourcing in Clinical Trials DACH 2022
Wednesday, November 30, 2022 – Thursday, December 1, 2022
Australasian Pharmaceutical Science Association (APSA) and Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists (ASCEPT) 2022 Joint Conference
Tuesday, November 29, 2022 – Friday, December 2, 2022
Immunic’s Multiple Sclerosis R&D Webcast
Thursday, November 17, 2022
Mechanistic Impact of Different Ligand Scaffolds on FXR Modulation Suggests Avenues to Selective Modulators
Jan Heering, Nathalie Jores, Whitney Kilu, Espen Schallmayer, Evelyn Peelen, Andreas Muehler, Hella Kohlhof, Daniel Vitt, Verena Linhard, Santosh L. Gande, Apirat Chaikuad, Sridhar Sreeramulu, Harald Schwalbe, Daniel Merk
ACS Chemical Biology
Published: November 1, 2022
https://doi.org/10.1021/acschembio.2c0059938th Congress of European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS)
Wednesday, October 26, 2022 – Friday, October 28, 2022
19th International Celiac Disease Symposium (ICDS)
Wednesday, October 19, 2022 – Saturday, October 22, 2022
IMU-856: Phase 1 SAD/MAD Data in Healthy Human Subjects
Tuesday, September 20, 2022
B & T Cell-Mediated Autoimmune Disease Drug Development Summit
Tuesday, July 26, 2022 – Thursday, July 28, 2022
16th World Immune Regulation Meeting
Wednesday, July 6, 2022 – Saturday, July 9, 2022
A double-blind, randomized, placebo-controlled phase 2 trial evaluating the selective dihydroorotate dehydrogenase inhibitor vidofludimus calcium in relapsing-remitting multiple sclerosis
Robert J. Fox, Heinz Wiendl, Christian Wolf, Nicola De Stefano, Johann Sellner, Viktoriia Gryb, Konrad Rejdak, Plamen Stoyanov Bozhinov, Nataliya Tomakh, Iryna Skrypchenko, Andreas R. Muehler
Annals of Clinical and Translational Neurology
Published: June 14, 2022
https://doi.org/10.1002/acn3.5157413th International Congress on Autoimmunity
Friday, June 10, 2022 – Monday, June 13, 2022
A Pilot Study of Vidofludimus Calcium for Treatment of Primary Sclerosing Cholangitis
Elizabeth J. Carey, John Eaton, Mitchell Clayton, Andrea Gossard, Sara Iqbal, Hamid Ullah, Nan Zhang, Richard Butterfield, Keith D. Lindor
Hepatology Communications
Published: March 3, 2022
https://doi.org/10.1002/hep4.192617th Congress of ECCO (European Crohn’s and Colitis Organization)
Wednesday, February 16, 2022 – Saturday, February 19, 2022
IMU-935: Phase 1 SAD/MAD Data in Healthy Human Subjects and Preclinical Update
Tuesday, December 14, 2021
37th Congress of European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS)
Wednesday, October 13, 2021 – Friday, October 15, 2021
B&T Cell-Mediated Autoimmune Disease Drug Development Summit
Wednesday, October 6, 2021
50th Annual European Society for Dermatological Research (ESDR) Meeting
Wednesday, September 22, 2021 – Saturday, September 25, 2021
Virtual R&D Day: Update on the Preclinical and Clinical Development of IMU-935
Monday, July 12, 2021
The International Federation of Psoriasis Association’s 6th World Psoriasis & Psoriatic Arthritis Conference 2021
Wednesday, June 30, 2021 – Saturday, July 3, 2021
2021 Virtual AAN Annual Meeting
Saturday, April 17, 2021 – Thursday, April 22, 2021
Clinical Relevance of Intestinal Barrier Dysfunction in Common Gastrointestinal Diseases
Andreas Muehler, Jason R. Slizgi, Hella Kohlhof, Manfred Groeppel, Evelyn Peelen, Daniel Vitt
World Journal of Gastrointestinal Pathophysiology
Published: December 12, 2020
https://doi.org/10.4291/wjgp.v11.i6.114MSVirtual2020 / 8th Joint ACTRIMS-ECTRIMS Meeting
Friday, September 11, 2020 – Sunday, September 13, 2020
Immunic’s Inaugural Virtual R&D Day
Tuesday, May 19, 2020
Vidofludimus Calcium, a Next Generation DHODH Inhibitor for the Treatment of Relapsing-Remitting Multiple Sclerosis
Andreas Muehler, Evelyn Peelen, Hella Kohlhof, Manfred Gröppel, Daniel Vitt
Multiple Sclerosis and Related Disorders
Published: May 6, 2020
https://doi.org/10.1016/j.msard.2020.102129Safety, Tolerability and Pharmacokinetics of Vidofludimus Calcium (IMU-838) After Single and Multiple Ascending Oral Doses in Healthy Male Subjects
Andreas Muehler, Hella Kohlhof, Manfred Groeppel, Daniel Vitt
European Journal of Drug Metabolism and Pharmacokinetics
Published: May 2, 2020
https://doi.org/10.1007/s13318-020-00623-7Design, Rationale and Baseline Characteristics of the Randomized Double-blind Phase II Clinical Trial of Vidofludimus calcium (IMU-838) in Relapsing-Remitting Multiple Sclerosis (4558)
Robert Fox, Heinz Wiendl, Nicola De Stefano, Johann Sellner, Andreas Mühler
Neurology
Published: April 14, 2020IBD Innovate Conference: Product Development for Crohn’s and Colitis
Wednesday, December 4, 2019
New YorkUnited European Gastroenterology Week (UEGW)
Tuesday, October 22, 2019
Barcelona, SpainThe Selective Oral Immunomodulator Vidofludimus in Patients with Active Rheumatoid Arthritis: Safety Results from the COMPONENT Study
Andreas Muehler, Hella Kohlhof, Manfred Groeppel, Daniel Vitt
Drugs in R&D
Published: October 16, 2019
https://doi.org/10.1007/s40268-019-00286-zCongress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) 2019
Wednesday, September 11, 2019
Stockholm, SwedenGI Inflammatory Diseases Summit (GIIDS)
Monday, June 24, 2019
Boston